GSM5983930: RCH sh2; Homo sapiens; ATAC-seq
Five million cells from actively growing NSD2 High and Low cell lines were crosslinked with 2% PFA and quenched with glycine. Following crosslinking, cells were lysed, DNA digested and proximally ligated following Arima Genomics' Hi-C kit User Guide for Mammalian Cell Lines by the NYU Langone Genome Technology Center. Hi-C libraries were generated using Arima HiC Kit along with Swift 2S Plus Kit and Swift Indexing Kit following Arima-HiC Kit Library Preparation using Swift Biosciences(R) Accel-NGS(R) 2S Plus DNA Library Kit User Guide.