Evaluating the changes that different bacteria species have upon a mouse model of arthritis's intestinal microbiome.
Mice were administered different lines of bacteria, some of which had immune-suppressive qualities, some of which had immune exacerbating qualities, and the impact upon the immune system in the context of arthritis was evaluated. The microbiome analysis aims to correlate the microbial changes with immune changes and disease severity in predicting the treatment strategies for arthritis using microbial therapeutics. Stool and gut section samples were collected between June 2015 and September 2017.  16s libraries and subsequent sequencing files were generated between January 2017 and December 2017.