Sample_B14_10009873
We utilized corresponding cancer free polyps (non-aggressive and aggressive) polyp samples and cancer adjacent polyps. We performed whole genome sequencing and RNA-sequencing on 100 patients, representing over 300 tissues. DNA libraries were prepared at BGI from 10ng input genomic DNA (representing roughly 2000 nuclei) from each tissue using the NEB kit (NEBNext Ultra II FS DNA Library Prep Kit for Illumina (https://www.neb.com/products/e7805-nebnext-ultra-ii-fs-dna-library-prep-kit-for-illumina#Product%20Information). Samples were sequenced on the BGISEQ500 by 100bp paired end.