Human sapiens
Total RNA was extracted from control- and curcumin-treated groups of cells using TRIzol. PCR amplification, product purification and quantification, and sequencing were carried out with the Illumina HiSeq 2500 platform. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were used to estimate the impacts of the differentially expressed genes (DEGs) and identify the affected signalling pathways. Then, proteinprotein interaction (PPI) network and sub-PPI network analyses were conducted using the STRING database.