Whole exome sequencing of 62 multiple myeloma patients at diagnosis and progression
WES libraries were constructed from genomic DNA using the Nextera Rapid Capture Exome (Illumina, San Diego, California, USA) which targets a genomic footprint of specific coverage of 37 Mb of exonic content. Paired-end sequencing was carried out with HiSeq SBS kit V4-250 cycles on Hiseq 2500 (Illumina).