joint analysis of metabolome and transcriptome in system Xc- regulating glucose deprivation-induced cell death
Total RNA was extracted using mirVana RNA Isolation Kit (Ambion) following manufacturer's instructions. The qualified data were subjected to the subsequent analysis. Differential transcripts upon specific treatments were defined by P-value0.05 and foldchange2. Gene ontology (GO) analysis and KEGG enrichment were done by Hypergeometric Distribution Test as previously described.
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