GSM5069296: RBE_TNF, scATAC-seq; Homo sapiens; ATAC-seq
This is achieved by transposing nuclei in a bulk solution; then using a microfluidic chip, the nuclei are partitioned into nanoliter-scale Gel Beadsin-emulsion (GEMs). A pool of ~750,000 10x Barcodes is sampled to separately and uniquely index the transposed DNA of each individual nucleus. Libraries are generated and sequenced, and 10x Barcodes are used to associate individual reads back to the individual partitions, and thereby, to each individual nucleus.