Purified mtDNA in the PolG mouse liver
The shotgun genomic libraries were prepared with the Hyper Library construction kit from Kapa Biosystems with no PCR amplification (Roche). The libraries were quantitated by qPCR and sequenced on one lane for 151 cycles from each end of the fragments on a HiSeq 4000 using a HiSeq 4000 sequencing kit version 1.