Characterization of the intestinal microbiota in men who have sex with men with HIV infection
This study enrolled four participant groups: uninfected MSM, Recent HIV-1 infection (RHI) MSM, MSM on ART, and non-MSM healthy controls, with 30 individuals in each group. We utilized 16S rDNA amplicon sequencing to analyze fecal microbiota, and employed Luminex multiplex assays to measure plasma markers for microbial translocation (LBP, sCD103) and the inflammatory marker CRP.