ATAC-seq of K562 engineered to have TetO reporters and rTetR-VP48 constitutively expressed
Bulk omni-ATAC was performed as in (Corces et al. 2017) with 50,000 cells and two biological replicates per sample. Libraries were sequenced 2x36 with an NextSeq 500/550 High Output v2.5 75 cycles kit (Illumina, 20024906) on a NextSeq 550.