GSM7846291: VEXAS syndrome 2 [2]; Homo sapiens; RNA-Seq
We included patients with skin lesions of VEXAS syndrome (n=6), myelodysplasia-cutis (n=4), idiopathic sweet syndrome (n=5) and leukemia cutis (n=5). Five healthy controls (HC) were recruited for skin biopsy from plastic breast surgery waste. The study was approved by the by our institutional ethic committee, and all patients were consented. Total RNA was automatically extracted from one lesional formaldehyde-fixed and paraffin-embedded skin biopsy for each patient and control using the Maxwell RSC RNA FFPE kit according to the manufacturer's protocol. SMARTer® Stranded Total RNA-Seq Kit v3-Pico Input Mammalian Kit from Takara