Transcriptome of CD4 T cell subsets: Sample SCOPE_3215_CMX5negR7posR6pos
Memory CD4 T cell samples from 5 people with HIV (PWH) with long-term antiretroviral therapy (ART) were subjected to Focused Interrogation of cells by Nucleic acid Detection and Sequencing (FIND-seq). Resulting transcriptome data were pre-processed and analyzed in the CLC Genomics Workbench v.21.0.3 to identify gene expression signatures of HIV DNA+ cells. To explore the origin of these signatures, they were compared with the transcriptomes of defined CD4 T cell subsets derived from 9 ART-treated PWH.