HiC of Schmidtea polychroa: wild type
Chromatin conformation capturing was done using the ARIMA-HiC High Coverage Kit (A101030-ARI) following the Arima documentation. Crosslinked gDNA was digested with a cocktail of four restriction enzymes. The 5-overhangs were filled in and labelled with biotin. Spatially proximal digested DNA ends were ligated, and the ligated biotin containing fragments were enriched and went for Illumina library preparation, following the ARIMA user guide for Library preparation using the Kapa Hyper Prep kit (A160139 v00).