Dovetail chicago library
Chicago library (Putnam et al., 2016) and Dovetail HiC library (Lieberman-Aiden et al., 2009) were prepared where chromatin was fixed in place with formaldehyde in the nucleus and then extracted fixed chromatin was digested with DpnII and the DNA was then sheared to ~350bp mean fragment size and sequencing libraries were generated using NEBNext Ultra enzymes and Illumina-compatible adapters.