RNA-seq of Alzheimer's genes based on LTP.
Hippocampal slices of APP/PS1 mouse were subjected to field excitatory postsynaptic potentials recordings, and pyramidal neurons in the CA1 region were collected 60 minutes after high frequency stimulation (HFS) when LTP was formed, after which the collected neurons were subjected to RNA extraction and RNA-seq.cDNA library construction and sequencing were performed by  Beijing Genomics institution Co., Ltd using a BGISEQ500 sequencer.