WGBS of human DNA extracted from nasal epithelial cells
DNA (250 ng) from participants in the URECA and COAST cohorts was transferred to the University of Chicago Genomics Core Facility. Bisulfite conversion and sequencing were conducted using the EZ DNA Methylation-Gold Kit library prep and the Swift Biosciences Accel-NGS Methyl-seq DNA library kit, respectively. Samples were sequenced to a minimum of 330 million reads on the Illumina NovaSEQ6000 (S4 flowcell).