WGS - Homo sapiens - adult male
500-750ng of genomic DNA was sheared to 400-600bp using the Covaris LE220-plus instrument  (Covaris).  Size selection was performed post fragmentation. Samples were then processed using the  Kapa Hyper Prep kit for End-Repair, A-Tailing and Ligation of IDT (Integrated DNA Technologies) unique  dual- indexed adapters according to the Kapa protocol to create a final PCR-free library.