Whole exome sequencing on cases of Multisystem Inflammatory Syndrome in Children (MIS-C) related to COVID-19 from Brazil
One microgram of genomic DNA was used for WES library preparation. The libraries were subjected to next-generation sequencing (2×150 bp) on the NovaSeq 6000 platform. Around 1% of the reads, representing off-target regions, were excluded. The mapping files (BAM) were obtained using the SAMTools program (v1.15). Only target regions with ten or more reads were retained in the study.