Targeted_next-generation_sequencing_of_Felis_catus: 44H20_HCM_Across_Breed_Study_tNGS
The study consists of samples from 44 cats (23 controls, 21 with HCM) of diverse breeds, representing 21 non-pedigree cats (DSH) and pedigree breeds (4 Bengal, 8 British shorthair, 1 British longhair, 6 NFC, 3 Ragdoll, and 1 Maine coon), genomic DNA samples were subjected to targeted next-generation sequencing using a feline HCM gene panel. This panel, based on 18 candidate genes implicated in human cardiomyopathies (equivalent to Illumina TrueSight Cardio Panel), was sequenced at the Animal Health Trust using Roche NimbleGen SeqCap Target Enrichment on a MiSeq Illumina Platform.