RNA-Seq of mus musculus: heart tissue
In order to explore the possible mechanism of FTO-m6A pathway in the improvement of cardiac hypertrophy by exercise intervention, we performed MeRIP-seq and RNA-seq high-throughput sequencing on myocardial tissues of mice with cardiac hypertrophy and exercise intervention, and analyzed the potential target genes involved in energy metabolism in the differential genes.  Overall design: Comparative gene expression profiling of m6A MeRIP-seq data from cardiac muscle samples from three normal C62, three TAC-induced cardiac hypertrophy sedentary groups, and three TAC-induced cardiac hypertrophy exercise groups.