Hi-C Sequencing of Patagonian toothfish
The dovetail Hi-C library was prepared according to the manufacturers instructions (Dovetail Hi-C Library kit). Chromatin was captured by chromatin capture beads and then digested with restriction enzyme. Its end was filled-in with biotin and ligated to form Intra-aggregated DNA. Sequencing is performed using an Illumina NovaSeq 6000 system following provided protocols for 2x150 sequencing.