MEC-1 10_3.19 - AID Knock-Out - Idelalisib Resistant
Targeted whole-exome sequencing. Paired fastq reads were then aligned with BWA using human GRCh38/hg38 as the reference genome. Single nucleotides were assessed using Strelka2. Variants in vcf format were further annotated using CEQer. Structural variants were analyzed using Manta and copy number abnormalities using CopywriteR v.2.22.0.