Small intestinal organoids derived from Fpr2f/f mice were treated with 1 μM MMK-1 for 5 days. 0.1% DMSO was used as the vehicle control.  Total RNA was extracted using Trizol. The RNA libraries for RNA-seq were constructed using the VAHTS Universal V10 RNA-seq Library Prep Kit (Premixed Version) according to the manufacturer's instructions. RNA library construction, RNA-seq, and transcriptome analysis were conducted by OE Biotech Co., Ltd. (Shanghai, China).