The whole-transcriptome sequencing (RNA-Seq) was conducted by Shanghai Biozeron Biotechnology Co., Ltd., and the Illumina NovaSeq 6000 platform was used to generate data and then analyzed by the Cloud Platform of Biozeron. Software Trimmomatic was used to analyze the quality of RNA-Seq data, and high-quality reads were aligned with the genome of A. hydrophila XS-91-4-1 by Rockhopper.