Briefly, m6A RNA immunoprecipitation was performed with the GenSeqTM m6A-MeRIP Kit (GenSeq Inc., Cyberjaya, Malaysia) by following the manufacturer's instructions. Both the input samples without immunoprecipitation and the m6A IP samples were used for RNA-seq library generation. The library quality was evaluated with Bioptic Qsep100 Analyzer(Bioptic lnc.,Taiwan,China). Library sequencing was performed on an illumina NovaSeq instrument with 150bp paired-end reads.