Native ChIP was performed as described (Martire et al. 2019). Briefly, A673 cells were harvested and treated with Mnase, resulting in a population consisting mainly of mono- to trinucleosomes. Chromatin was isolated and used for ChIP according to standard procedures. Cross-linked ChIP was performed as described (Martire et al. 2019). Briefly, A673 cells were cross-linked with 1% PFA. Chromatin was then sheared to 200-700 bp. For both procedures, chromatin was isolated and used for ChIP according to standard procedures. ChIP-seq libraries were constructed according to the NEBNext protocol.