10x Genomics Chromium Next GEM Single-Cell 5 kit v.1.1, Chromium Single Cell V(D)J enrichment kit (Human T Cell) and Chromium Single Cell 5 Feature Barcode Library Kit were used to generate GEX, VDJ and Cite-seq libraries according to the manufacturers protocol. The cDNA libraries were sequenced on a MGITech MGISEQ2000RS platform using MGIEase V2 chemistry, targeting a median sequencing depth of 50,000, 5,000 and 10,000 read pairs per cell for gene expression, TCR, and combined dCODE and TotalSeq-C libraries,respectively.