Raw Illumina reads of Paracoccus LL1
the sequencing library is prepared by random fragmentation of the DNA or cDNA sample, followed by 5 and 3 adapter ligation. This library is loaded into a flow cellwhere fragments are captured on a lawn of surface-bound oligos complementary to the library adapters. As all 4 reversible, terminator-bound dNTPs are present during each sequencing cycle, natural competition minimizes incorporation bias and greatly reduces raw error rates