GSM9568148: WT_Vehicle_1; Homo sapiens; ATAC-seq
Nuclei extraction from vehicle-control, palbociclib-resistant and abemaciclib-resistant MCF7 cells, either ER-WT or ER-mutant, and transposition reactions were performed aspreviously  described in "Nardone, A. et al. A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer. Cancer Res 82, 3673-3686 (2022)" Libraries were amplified as described in "Buenrostro, J.D., Giresi, P.G., Zaba, L.C., Chang, H.Y. & Greenleaf, W.J. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods 10, 1213-8 (2013)"