Census-seq low-coverage WGS of 23-donor neural progenitor cell village comprising 12 donors with 16p11.2 deletion and 11 controls, passage 2, day 6, well 3, untreated control
A 23-donor human iPSC-derived neural progenitor cell village comprising 12 donors with 16p11.2 deletion and 11 controls was pooled at equal proportions. Post-baseline samples were maintained in triplicate wells, passaged every 5 days for 15 days, and harvested for genomic DNA extraction and Census-seq low-coverage whole-genome sequencing to measure donor composition and proliferation effects.