GSM9644911: CBE OT 1 Rep 4; Homo sapiens; OTHER
For mouse tissues only striatum extraction; DNeasy DNA extraction; amplicon sequencing with Nextera XT library consruction; MiSeq; CRISPResso2 alignment and quantification of base editing and allele frequency Samples for DNA editing were extracted using Qiagen's DNeasy DNA extraction kit For Illumina Miseq experiments, libraries were constructed with the nextera XT indexing primer kits as per manufacturer's instructions Targeted genomic and exon high throughput sequencing with nextera indexing primers