WES of Homo sapiens:male
Whole-exome was captured by SureSelect Human All Exon Kit (Agilent), followed high-throughput sequencing by HiSeq2000 sequencer (Illumina Inc.). Genomic reads were aligned for SNP calling and further analysis for identification of deleterious variants which are predicted by multiple commonly used programs, such as MutationTaster, Polyphen-2 and SIFT.