BCL-2 overexpression attenuates p53 stabilization and activation following RiBi inhibitors treatment
BCL-2 overexpression attenuates p53 stabilization and activation following RiBi inhibitors treatment
Following pre-treatment with doxycycline 1Âµg/ml for 96 hours, SUDHL-5 cells transfected with empty vector (Empty) or BCL-2 TET-ON inducible system (BCL-2), were incubated for 6h with Doxorubicin 100nM, Actinomycin D 2.5nM, CX-5461 2500nM  Total RNA extraction was performed using ZYMO RESEARCH Quick-RNA MiniPrep kit  Illumina Hi-Seq 2000 with paired-end 2 x 51-bp read lengths 