GENOMIC
Take 1-4 g of DNA sample and fragment it using the Covaris S220 sonicator to recover 300-700 bp fragments. Use streptavidin-coated magnetic beads to capture DNA fragments that have interaction relationships for library construction. After the library is constructed, use both Qubit 3.0 and the GX platform to measure the library concentration and insert size. Employ Q-PCR to accurately quantify the effective concentration of the library to ensure its quality. The constructed library will be sequenced using the Illumina NovaSeq 6000 with a read length of PE150.