Repli-HiC-K562_WT_RepliHiC_resource2
Libraries were constructed by the Repli-HiC2 strategy. Briefly, after dox treatment for 24h and IAA treatment for 6h, wide-type K562 cells were treated with BrdU for 15 min and sorted in mClover-negative group, fixed, digested by HaeIII, dA-tailing, and ligated with biotinylated linkers. Fragmentated DNA was enriched by anti-BrdU and then biotin. After that, DNA was tagged with adapters and sequenced. Biological replicate two.