Visium HD spatial transcriptomics of WT post-EV injection recovery mouse brain sample 1
10x Genomics Visium HD spatial transcriptomic library prepared from FFPE mouse brain tissue using the Visium HD Spatial Gene Expression for FFPE library v1 - Mouse (6.5 mm) kit and sequenced on an Illumina NovaSeq 6000 platform by Macrogen. Raw FASTQ files are submitted to SRA; downstream spatial transcriptomic processing was performed using the standard Visium HD binned-output workflow. Supplementary recovery dataset; mouse received the same 12-week intragingival injection regimen of Aggregatibacter actinomycetemcomitans-derived extracellular vesicles followed by a 3-week spontaneous recovery period without additional EV injection; injections started on 2024-08-20; brain tissue was collected on 2024-12-03.