R18851 - CUT&Tag, H3K27ac (HCR, Female, Rest, Sedentary)
CUT&Tag targeting histone modification H3K27ac was performed on nuclei isolated from frozen gastrognemius of High Capacity Runner (HCR) and Low Capacity Runner (LCR) following a 6-week aerobic training protocol (Trained vs Sedentary). After the training period, all rats were subject to an acute exercise bout (treadmill test), with tissue collected at rest (Rest), 1/2-maximum exercise (Half-Max), maximum exercise (Max), and after 1 hour of recovery (Rec).