Whole Exome Sequencing of Family Quartet (Father, Mother, Proband, and Unaffected Sibling) to Investigate Genetic Variants Associated with Alport Syndrome
Whole exome sequencing (WES) was performed using the Agilent SureSelect XT Human All Exon v6 + UTR kit for targeted capture of exonic regions. Sequencing libraries were prepared following the manufacturers protocol and sequenced on an Illumina HiSeq 4000 using 2x150bp paired-end reads.