WES adult female pre-chemotherapy cancer tissue
The optimized DNA/RNA extraction protocol using the AllPrep DNA/RNA kit (Qiagen) was followed. Whole-exome sequencing (WES) libraries were prepared using enrichment kits (Agilent SureSelect All Exon V6) according to the manufacturer's instructions. Libraries were pooled and sequenced on the Illumina NovaSeq 6000 platform with 2x150 bp paired-end reads.