title: Updated reference genome sequence and annotation of Mycobacterium bovis AF2122/97
organism: Mycobacterium tuberculosis variant bovis AF2122/97
description: We report an update to the reference genome sequence of the bovine tuberculosis bacillus Mycobacterium bovis AF2122/97 generated using an integrative multi-'omics approach. Updates include 42 new coding sequences, 14 modified annotations, 26 single nucleotide polymorphisms and disclosure that the RD900 locus, previously described as absent from the M. bovis AF2122/97 genome, is in fact present.
attributes.tag: ENA first public
attributes.value: 2016-12-06
attributes.tag: ENA last update
attributes.value: 2016-11-30
attributes.tag: External Id
attributes.value: SAMEA18127918
attributes.tag: INSDC center alias
attributes.value: School of Veterinary Medicine
attributes.tag: INSDC center name
attributes.value: School of Veterinary Medicine
attributes.tag: INSDC first public
attributes.value: 2016-12-06T17:02:11Z
attributes.tag: INSDC last update
attributes.value: 2016-11-30T15:40:39Z
attributes.tag: INSDC status
attributes.value: public
attributes.tag: Submitter Id
attributes.value: AF2122_1_R2
attributes.tag: collection date
attributes.value: 1997
attributes.tag: geographic location (country and/or sea)
attributes.value: United Kingdom
attributes.tag: host health state
attributes.value: diseased
attributes.tag: host scientific name
attributes.value: Bos taurus
attributes.tag: isolate
attributes.value: AF2122/97
attributes.tag: isolation source
attributes.value: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection.
attributes.tag: sample name
attributes.value: AF2122_1_R2