organism: Homo sapiens
description: The mixed sample 90:0 was mixed with 90% healthy female DNA and 10% Down syndrome DNA. The sample was diluted to around 20 million molecules. This means that each molecule has a unique starting position in the genome, i.e. it is unique with a high probability. The mixed library was then amplified and sequenced until saturation that is each molecules is seen preferably at least two times. It is then possible to bioinformatically remove molecule copies. The idea is that all or most molecules before amplification should be seen after sequencing, and the bias from amplification should be removed.
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