title: CGFF2
organism: Nakaseomyces glabratus
attributes.tag: Alias
attributes.value: CGFF2
attributes.tag: Description
attributes.value: In this work a phenotypic screening over a cohort of clinical Candida glabrata isolates was undertaken leading to the identification of an isolate, named FFUL887, which was recovered from the urinary tract and that was found to be resistant to both fluconazole and voriconazole. To better understand the molecular mechanisms underlying the azole-resistance phenotype of the FFUL887 strain its genome sequence was obtained, annotated and compared with the one of the reference strain CBS138, susceptible to the two above mentioned azoles and having an intestinal origin. Besides providing clues to mechanisms underlying acquisition of azole resistance inside the host, our results also provide insights into the different responses evolved by C. glabrata in the colonization of different niches.
attributes.tag: ENA checklist
attributes.value: ERC000011
attributes.tag: INSDC center name
attributes.value: Technische Universitat Munchen - WZW
attributes.tag: INSDC first public
attributes.value: 2017-10-23T17:03:30Z
attributes.tag: INSDC last update
attributes.value: 2017-02-15T12:23:42Z
attributes.tag: INSDC status
attributes.value: public
attributes.tag: SRA accession
attributes.value: ERS1559825
attributes.tag: Sample Name
attributes.value: ERS1559825
attributes.tag: Title
attributes.value: Sequencing and comparative genomics of Candida glabrata isolate FFUL887
attributes.tag: isolate
attributes.value: FFUL887