organism: Mus musculus
description: Sham exposed - These male mice received no charged-particle radiation, but were subjected to minor ammounts of background electromagnetic radiation from activated metals in the beam line of NASA&apos;s space radiation laboratory
attributes.tag: common name
attributes.value: House Mouse
attributes.tag: dev stage
attributes.value: Adult
attributes.tag: material
attributes.value: Whole Hippocampus
attributes.tag: sample name
attributes.value: 807-5005
attributes.tag: scientific name
attributes.value: Mus Musculus
attributes.tag: sex
attributes.value: male
attributes.tag: submission description
attributes.value: 6mo. old male C57bl/6j mice were exposed to 0.5 Gy of 1H (600MeV/n) followed by 0.1Gy of 16O (600MeV/n). 9 mo. later, mice were sacrificed, their whole hippocampi were collected, snap frozen, and genomic DNA was isolated. DNA was processed and sequenced against a custom targeted array for genes involved in oxidative stress, inflammation, and immediate early genes. SNP analyses were conducted and compared between sham and irradiated animals.
attributes.tag: submission identifier
attributes.value: GSB-10012
attributes.tag: submission title
attributes.value: Late effects of 1H + 16O on hippocampal mutagenesis