title: 15_S15
organism: Escherichia coli
description: levofloxacin
attributes.tag: strain
attributes.value: WO153
attributes.tag: isolate
attributes.value: NA
attributes.tag: host
attributes.value: NA
attributes.tag: isolation_source
attributes.value: NA
attributes.tag: collection_date
attributes.value: 2016/2018
attributes.tag: geo_loc_name
attributes.value: NA
attributes.tag: altitude
attributes.value: NA
attributes.tag: biomaterial_provider
attributes.value: NA
attributes.tag: culture_collection
attributes.value: NA
attributes.tag: depth
attributes.value: NA
attributes.tag: env_broad_scale
attributes.value: NA
attributes.tag: genotype
attributes.value: NA
attributes.tag: host_tissue_sampled
attributes.value: NA
attributes.tag: identified_by
attributes.value: NA
attributes.tag: lab_host
attributes.value: NA
attributes.tag: lat_lon
attributes.value: NA
attributes.tag: mating_type
attributes.value: NA
attributes.tag: passage_history
attributes.value: NA
attributes.tag: samp_size
attributes.value: NA
attributes.tag: serotype
attributes.value: NA
attributes.tag: serovar
attributes.value: NA
attributes.tag: specimen_voucher
attributes.value: NA
attributes.tag: temp
attributes.value: NA
attributes.tag: sample_type
attributes.value: cell culture
attributes.tag: id_espinoza-et-al
attributes.value: levofloxacin|dmso-9|1|2|9.0|15|s15
attributes.tag: run
attributes.value: 9.0
attributes.tag: id_jira
attributes.value: SOLEXASEQ-1122
attributes.tag: id_orourke-et-al
attributes.value: R09_Levofloxacin_BR2
attributes.tag: id_sequencing-number
attributes.value: S15
attributes.tag: id_barcode-number
attributes.value: 15
attributes.tag: biological_replicate
attributes.value: 2
attributes.tag: sample-category
attributes.value: pure_compound
attributes.tag: sample-category_encoding
attributes.value: 1
attributes.tag: cpd_local
attributes.value: levofloxacin
attributes.tag: cpd_universal
attributes.value: levofloxacin
attributes.tag: ctrl_local
attributes.value: dmso-9
attributes.tag: ctrl_universal
attributes.value: dmso
attributes.tag: og_moa
attributes.value: dna-gyrase
attributes.tag: moa
attributes.value: dna-synthesis
attributes.tag: moa_encoding
attributes.value: 5
attributes.tag: moa_color
attributes.value: #57db5f
attributes.tag: jcvi_sub-moa
attributes.value: dna-enzyme-inhibition
attributes.tag: jcvi_sub-moa_encoding
attributes.value: 1.0
attributes.tag: neu_sub-moa
attributes.value: dna-enzyme-inhibition
attributes.tag: neu_sub-moa_description
attributes.value: inhibit DNA gyrase and topo IV (linking them to DNA), leading to blocking of replication fork and eventual DNA strand breaks
attributes.tag: neu_sub-moa_encoding
attributes.value: 1.0
attributes.tag: gene_target_identifiers
attributes.value: ['P43700', 'P43702']
attributes.tag: gene_target_description
attributes.value: DNA gyrase subunit A, DNA topoisomerase 4 subunit A
attributes.tag: ORourke_et_al
attributes.value: False
attributes.tag: Espinoza_et_al
attributes.value: True
attributes.tag: BioSampleModel
attributes.value: Microbe, viral or environmental