title: HudsonAlpha_ChipSeq_T-47D_ERalpha_a_BPA_100nM_v041610.2
organism: Homo sapiens
attributes.tag: source_name
attributes.value: T-47D
attributes.tag: biomaterial_provider
attributes.value: ATCC
attributes.tag: datatype
attributes.value: ChipSeq
attributes.tag: datatype description
attributes.value: Chromatin IP Sequencing
attributes.tag: antibody antibodydescription
attributes.value: Rabbit affinity purified polyclonal antibody. Epitope is the C-terminus of human estrogen receptor alpha (ESR1). Recommended for detection of estrogen receptor of m, r and h origin by WB, IP, IF, IHC(P) and ELISA. Antibody Target: ESR1
attributes.tag: antibody targetdescription
attributes.value: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq)
attributes.tag: antibody vendorname
attributes.value: Santa Cruz Biotechnology
attributes.tag: antibody vendorid
attributes.value: sc-543
attributes.tag: treatment description
attributes.value: 1 h with 100 nM Bisphenol A (Myers)
attributes.tag: controlid
attributes.value: SL1490
attributes.tag: labexpid
attributes.value: SL1877,SL1493
attributes.tag: softwareversion
attributes.value: MACS
attributes.tag: antibody antibodydescription
attributes.value: Rabbit affinity purified polyclonal antibody. Epitope is the C-terminus of human estrogen receptor alpha (ESR1). Recommended for detection of estrogen receptor of m, r and h origin by WB, IP, IF, IHC(P) and ELISA. Antibody Target: ESR1
attributes.tag: antibody targetdescription
attributes.value: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq)
attributes.tag: antibody vendorname
attributes.value: Santa Cruz Biotechnology
attributes.tag: antibody vendorid
attributes.value: sc-543
attributes.tag: treatment
attributes.value: BPA_100nM
attributes.tag: treatment description
attributes.value: 1 h with 100 nM Bisphenol A (Myers)
attributes.tag: protocol
attributes.value: v041610.2
attributes.tag: protocol description
attributes.value: 2x10^7 cells, fragmentation by probe-in sonicator, one 15-cycle round of PCR (Myers)
attributes.tag: controlid
attributes.value: SL1490
attributes.tag: labexpid
attributes.value: SL1877,SL1493
attributes.tag: replicate
attributes.value: 1,2
attributes.tag: softwareversion
attributes.value: MACS