title: Stanford_ChipSeq_K562_CDP_(sc-6327)_IgG-rab
organism: Homo sapiens
attributes.tag: source_name
attributes.value: K562
attributes.tag: biomaterial_provider
attributes.value: ATCC
attributes.tag: lab
attributes.value: Stanford
attributes.tag: lab description
attributes.value: Snyder - Stanford University
attributes.tag: datatype
attributes.value: ChipSeq
attributes.tag: datatype description
attributes.value: Chromatin IP Sequencing
attributes.tag: cell
attributes.value: K562
attributes.tag: cell organism
attributes.value: human
attributes.tag: cell description
attributes.value: leukemia, "The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous leukemia in terminal blast crises." - ATCC
attributes.tag: cell karyotype
attributes.value: cancer
attributes.tag: cell lineage
attributes.value: mesoderm
attributes.tag: cell sex
attributes.value: F
attributes.tag: treatment
attributes.value: None
attributes.tag: treatment description
attributes.value: No special treatment or protocol applies
attributes.tag: antibody
attributes.value: CDP_(sc-6327)
attributes.tag: antibody antibodydescription
attributes.value: CDP (C-20) is an affinity purified goat polyclonal antibody raised against a peptide mapping at the C-terminus of CDP of mouse origin.
attributes.tag: antibody targetdescription
attributes.value: CDP (for CCAAT displacement protein) was identified as a repressor for tran- scription of developmentally regulated genes. It is a homeodomain protein that appears to compete with transcriptional activating proteins for binding to the promoter regions of various genes. CDP contains three cut repeats which function as DNA binding domains. It has been demonstrated that cut repeat domains have the capacity to bind to DNA in conjunction with or independently of homeodomain DNA binding. CDP has been shown to be the DNA-binding subunit of the HiNF-D complex, which contains cyclin A, Cdc2 and an Rb-related protein in addition to CDP. Histone expression is required for the transition to S phase in the cell cycle. The HiNF-D complex regulates the transcription of Histone H4, H3 and H1 genes, allowing cells to progress from G1 to S phase.
attributes.tag: antibody vendorname
attributes.value: Santa Cruz Biotechnology
attributes.tag: antibody vendorid
attributes.value: sc-6327
attributes.tag: control
attributes.value: IgG-rab
attributes.tag: control description
attributes.value: Input signal from Normal Rabbit IgG ChIP-seq.
attributes.tag: control
attributes.value: IgG-rab
attributes.tag: control description
attributes.value: Input signal from Normal Rabbit IgG ChIP-seq.
attributes.tag: controlid
attributes.value: wgEncodeEH001795
attributes.tag: labversion
attributes.value: PeakSeq1.0