title: P-0007823-T10-RD1_vs_NORMAL.vcf
organism: Homo sapiens
attributes.tag: Common Name
attributes.value: Human
attributes.tag: Scientific Name
attributes.value: Homo sapiens
attributes.tag: Subject
attributes.value: P-0007823
attributes.tag: Submission description
attributes.value: Targeted next-generation sequencing was performed in patients with IDH1 or IDH2 mutations. Here we describe 4 cases where mutant IDH isoform switching serves as a mechanism of acquired clinical resistance to mutant IDH inhibition.
attributes.tag: Submission identifier
attributes.value: GSB-587
attributes.tag: Submission title
attributes.value: Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition
attributes.tag: ENA-FIRST-PUBLIC
attributes.value: 2018-10-24
attributes.tag: ENA-LAST-UPDATE
attributes.value: 2018-10-24