title: Stanford_ChipSeq_MEL_CTCF_(SC-15914)_DMSO_2.0pct_std
organism: Mus musculus
attributes.tag: source_name
attributes.value: MEL
attributes.tag: biomaterial_provider
attributes.value: Weissman lab
attributes.tag: lab
attributes.value: Stanford-m
attributes.tag: lab description
attributes.value: Snyder - Stanford University
attributes.tag: datatype
attributes.value: ChipSeq
attributes.tag: datatype description
attributes.value: Chromatin IP Sequencing
attributes.tag: cell
attributes.value: MEL
attributes.tag: cell organism
attributes.value: mouse
attributes.tag: cell description
attributes.value: Leukemia (K562 analog)
attributes.tag: cell sex
attributes.value: M
attributes.tag: antibody
attributes.value: CTCF_(SC-15914)
attributes.tag: antibody antibodydescription
attributes.value: Goat polyclonal, epitope mapping near the C-terminus of CTCF of human origin. Antibody Target: CTCF
attributes.tag: antibody targetdescription
attributes.value: Transcriptional regulator with 11 highly conserved zinc finger domains. Depending on context, can bind a histone acetyltransferase (HAT)-containing complex and function as transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as transcriptional repressor. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation. Can dimerize, mediating long-range chromatin looping. When bound to chromatin, provides an anchor point for nucleosomes positioning. Involved in sister chromatid cohesion. Associates with both centromeres and chromosomal arms during metaphase and required for cohesin localization to CTCF sites.
attributes.tag: antibody vendorname
attributes.value: Santa Cruz Biotech
attributes.tag: antibody vendorid
attributes.value: sc-15914
attributes.tag: treatment
attributes.value: DMSO_2.0pct
attributes.tag: treatment description
attributes.value: 5 d with 2% Dimethyl sufloxide (DMSO) (Weissman)
attributes.tag: control
attributes.value: std
attributes.tag: control description
attributes.value: Standard input signal for most experiments.
attributes.tag: age
attributes.value: immortalized
attributes.tag: age description
attributes.value: Immortal cells
attributes.tag: control
attributes.value: std
attributes.tag: control description
attributes.value: Standard input signal for most experiments.
attributes.tag: controlid
attributes.value: wgEncodeEM002791
attributes.tag: labversion
attributes.value: PeakSeq1.0
attributes.tag: strain
attributes.value: Unknown
attributes.tag: strain description
attributes.value: Unknown strain origin