title: Stanford_ChipSeq_CH12_ZNF384_(HPA004051)_IgG-rab
organism: Mus musculus
attributes.tag: source_name
attributes.value: CH12
attributes.tag: biomaterial_provider
attributes.value: Weissman lab
attributes.tag: lab
attributes.value: Stanford-m
attributes.tag: lab description
attributes.value: Snyder - Stanford University
attributes.tag: datatype
attributes.value: ChipSeq
attributes.tag: datatype description
attributes.value: Chromatin IP Sequencing
attributes.tag: cell
attributes.value: CH12
attributes.tag: cell organism
attributes.value: mouse
attributes.tag: cell description
attributes.value: B-cell lymphoma (GM12878 analog)
attributes.tag: cell sex
attributes.value: F
attributes.tag: antibody
attributes.value: ZNF384_(HPA004051)
attributes.tag: antibody antibodydescription
attributes.value: Rabbit polyclonal generated using the immunogen: Zinc finger protein 384 recombinant protein epitope signature tag (PrEST)
attributes.tag: antibody targetdescription
attributes.value: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
attributes.tag: antibody vendorname
attributes.value: SIGMA
attributes.tag: antibody vendorid
attributes.value: HPA004051
attributes.tag: treatment
attributes.value: None
attributes.tag: treatment description
attributes.value: No special treatment or protocol applies
attributes.tag: control
attributes.value: IgG-rab
attributes.tag: control description
attributes.value: Input signal from Normal Rabbit IgG ChIP-seq.
attributes.tag: age
attributes.value: immortalized
attributes.tag: age description
attributes.value: Immortal cells
attributes.tag: control
attributes.value: IgG-rab
attributes.tag: control description
attributes.value: Input signal from Normal Rabbit IgG ChIP-seq.
attributes.tag: controlid
attributes.value: wgEncodeEM001939
attributes.tag: strain
attributes.value: B10.H-2aH-4bp/Wts
attributes.tag: strain description
attributes.value: Derived by inbreeding from selected F2 progeny of B10.A X B10.129