organism: Xenopus laevis
description: The establishment of cell lineages occurs via a dynamic progression of gene regulatory networks that underlie developmental commitment and differentiation. To investigate how microRNAs (miRs) function in this process, we compared miRs and miR targets at the initiation of the two major ectodermal lineages in Xenopus. To identify targets of miR-dependent translational control, we co-immunoprecipitated Argonaute-Ribonucleoprotein (Ago-RNP) complexes from early neural and epidermal ectoderm and sequenced the associated RNA.
attributes.tag: breed
attributes.value: NXR
attributes.tag: dev_stage
attributes.value: mid-gastrula
attributes.tag: sex
attributes.value: not applicable
attributes.tag: tissue
attributes.value: animal caps
attributes.tag: collected_by
attributes.value: A.K.S.
attributes.tag: BioSampleModel
attributes.value: Model organism or animal