title: 16S rRNA gene V4 - V5 healthy oral saliva microbiome samples
organism: Homo sapiens
description: The human oral cavity is inhabited by a diverse community of microbes known as the human oral microbiome. These microbes play a role in maintaining both oral and systemic health and as such have been proposed to be useful biomarkers of disease. However, to identify these biomarkers, we first need to determine the composition and variation of the healthy oral microbiome. Within this report we investigate the oral microbiome of 1049 healthy individuals to determine which genera and amplicon sequence variants are commonly found between individual oral microbiomes. We then further investigate how lifestyle, anthropometric, and dietary choices impact overall microbiome composition. Interestingly, the results from this investigation showed that while many features were significantly associated with oral microbiome composition no single biological factor explained a variation larger than 2%. These results indicate that future work on biomarker detection may be encourage by the lack of strong confounding factors.
attributes.tag: ENA-FIRST-PUBLIC
attributes.value: 2020-05-07T04:05:45Z
attributes.tag: ENA-LAST-UPDATE
attributes.value: 2020-05-06T16:44:45Z
attributes.tag: External Id
attributes.value: SAMEA6816705
attributes.tag: INSDC center name
attributes.value: DALHOUSIE UNIVERSITY
attributes.tag: INSDC first public
attributes.value: 2020-05-07T04:05:45Z
attributes.tag: INSDC last update
attributes.value: 2020-05-06T16:44:45Z
attributes.tag: INSDC status
attributes.value: public
attributes.tag: Submitter Id
attributes.value: 102050035
attributes.tag: collection date
attributes.value: 2009-01-01/2015-01-01
attributes.tag: common name
attributes.value: human
attributes.tag: environment (biome)
attributes.value: Human
attributes.tag: environment (feature)
attributes.value: Oral
attributes.tag: environment (material)
attributes.value: Saliva
attributes.tag: geographic location (country and/or sea)
attributes.value: Canada
attributes.tag: geographic location (latitude)
attributes.value: 44.682
attributes.tag: geographic location (longitude)
attributes.value: -63.7443
attributes.tag: human oral environmental package
attributes.value: human-oral
attributes.tag: investigation type
attributes.value: bacteria_archaea
attributes.tag: project name
attributes.value: Assessing the variation within the oral microbiome of healthy adults
attributes.tag: sample name
attributes.value: 102050035
attributes.tag: scientific_name
attributes.value: Homo sapiens
attributes.tag: sequencing method
attributes.value: Illumina