title: Model organism or animal sample for Ictalurus punctatus
organism: Ictalurus punctatus
description: Most organisms can experience various levels of hypoxia, and HIF1a has been believed to be the master regulator for responses to hypoxia. However, genes underlying hypoxia tolerance is not known. Here we report that the tumor suppressor gene TSC2 is most likely the master genetic switch for hypoxia tolerance using RNA-seq analysis. This finding has important implications in cancer biology as well as in considerations for therapeutic strategies against cancer.
attributes.tag: strain
attributes.value: Marion
attributes.tag: age
attributes.value: 2
attributes.tag: biomaterial_provider
attributes.value: Zhanjiang Liu
attributes.tag: sex
attributes.value: not determined
attributes.tag: tissue
attributes.value: Gill
attributes.tag: BioSampleModel
attributes.value: Model organism or animal