description: In an effort to better understand how Bacillus cereus 03BB102 acquires multidrug resistance, we examined the organisms response to elevated levels of different antibiotics (tetracycline, ciprofloxacin and vancomycin). In this study, we obtained eighteen isolates that showed resistance to selected antibiotics. Illumina and PacBio sequencing of the isolates and comparing them to the parental strain helped us to identify genomic changes during the stepwise in vitro generation of multidrug resistant isolates.
attributes.tag: strain
attributes.value: Tet2R1
attributes.tag: collection_date
attributes.value: 2021
attributes.tag: geo_loc_name
attributes.value: USA: NM, Los Alamos
attributes.tag: isolation_source
attributes.value: in vitro
attributes.tag: subsource_note
attributes.value: mutant derived from 03BB102
attributes.tag: sample_type
attributes.value: single colony
attributes.tag: BioSampleModel
attributes.value: Microbe, viral or environmental