title: 0.1% DMSO Treated Vehicle Control Rat Hepatocytes
organism: Rattus norvegicus
description: This sample comprises primary rat hepatocytes from male Sprague Dawley rats treated with 0.1% DMSO, serving as a higher concentration vehicle control within the study. The inclusion of this sample allows for the evaluation of dose-dependent effects of the vehicle itself on gene expression and splicing patterns. This comparison is essential to distinguish the specific responses triggered by xenobiotic treatments from those potentially induced by the vehicle at varying concentrations. This control is critical for understanding the broader impacts of DMSO on hepatic cells and for ensuring the robustness of the study's conclusions regarding xenobiotic influences.