title: 0.05% DMSO Treated Vehicle Control Rat Hepatocytes
organism: Rattus norvegicus
description: This sample consists of primary rat hepatocytes from male Sprague Dawley rats treated with 0.05% DMSO. It serves as a vehicle control to differentiate the effects of the vehicle from those of xenobiotic treatments in the study. The use of DMSO at this minimal concentration establishes a baseline to assess any vehicle-related changes in gene expression and splicing profiles, thereby providing a critical reference for interpreting the specific impacts of xenobiotic compounds. The cells were maintained under standard laboratory conditions and cryopreserved immediately after preparation to preserve their physiological and genetic integrity. This sample is part of a series exploring the modulation of gene expression and splicing under xenobiotic stress.