title: PML::RARA_WT_ATAC-seq_replicate_3_female
organism: Mus musculus
description: Bone marrow cells from C57Bl/6 mice were lineage-depleted and retrovirally transduced with murine stem cell virus (MSCV) vectors containing an internal ribosome entry site (IRES) followed by a GFP cDNA to allow for the purification of transduced cells. These vectors either contained no insert ("empty vector"), WT PML::RARA cDNA (PR or PML::RARA_WT), or a C88A mutant in the RARA domain of PML::RARA (C88A or PML::RARA_C88A-V5). Seven days following the transduction, GFP+ cells were flow-purified, and ATAC-seq was performed.
attributes.tag: strain
attributes.value: C57Bl/34
attributes.tag: age
attributes.value: 12 weeks
attributes.tag: collection_date
attributes.value: 2022-04-11
attributes.tag: geo_loc_name
attributes.value: USA
attributes.tag: sex
attributes.value: female
attributes.tag: tissue
attributes.value: Lineage-depleted bone marrow
attributes.tag: genotype
attributes.value: Wild-type
attributes.tag: BioSampleModel
attributes.value: Model organism or animal