organism: Homo sapiens
attributes.tag: isolate
attributes.value: Healthy human donor
attributes.tag: age
attributes.value: 34 years
attributes.tag: biomaterial_provider
attributes.value: Carl H. June, Perelman School of Medicine, University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Boulevard, Building 421, 8th Floor, Room 123, Philadelphia, PA. 19104-5156
attributes.tag: collection_date
attributes.value: 2024-08-13
attributes.tag: geo_loc_name
attributes.value: USA: Philadelphia, Pennsylvania
attributes.tag: sex
attributes.value: male
attributes.tag: tissue
attributes.value: Primary human T cells
attributes.tag: treatment
attributes.value: Multiplex adenine base editing of 20 distinct genes (CD3E, B2M, CIITA, PVR, CD52, ICAM1, CD58, PDCD1, CTLA4, CD5, RASA2, MED12, ZC3H12A, RC3H1, TET2, ARID1A, SMARCC1, SMARCA4, SMYD3, ADORA2A). The sample represents a pool of UTD T cells of one donor that have been 20-plex edited with either a low, medium, or high dose of gRNAs (5µg, 0.38µg, or 0.05µg per gRNA) at equal cell numbers.
attributes.tag: BioSampleModel
attributes.value: Human