Corrected SOD1 induced pluripotent stem cells
Homo sapiens
Zinc Finger Nuclease targeting the SOD1 locus was used to correct SOD1 A4V allele from iPSC generated by retroviral transduction of KLF4, SOX2, OCT4, and cMYC into dermal fibroblasts.
isolate
ipsc 39b SOD1 allele corrected by Zinc Finger Mediated Nuclease recombination
age
NA
biomaterial_provider
Kevin Eggan, Harvard University 7 Divinity Ave Cambridge MA
sex
female
tissue
Fibroblasts/iPSC
cell_type
iPSC
disease
ALS
sample_type
cell culture
SOD1 status
WT
BioSampleModel
Human