Generic sample from Homo sapiens
Homo sapiens
U87MG is a long established cell line derived from a human grade IV glioma that has been used in over 1,700 publications as of the beginning of year 2010.  A wide range of biological information is already known about this cell line. The U87MG cell line is known to have a highly aberrant genomic structure based on karyotyping, SKY, and FISH. However, these methods neither provide the resolution required to visualize the precise breakpoint of a translocation event, nor are they generally capable of identifying genomic microdeletions (deletions on the order of a megabase or less in size) in a whole genome survey of structural variation. Therefore, these more difficult to resolve mutations have yet to be assessed and it is the goal of this sequencing study to assess them.