CFBE cells with flip-in site -- Wild Type CFTR
Homo sapiens
These cells contain a flip-in site for introducing a construct of interest. This sample has a flip-in site within an open chromatin region of chromosome 8. This cell line has incorporated wild-type CFTR into this site. This cell line does not endogenously express CFTR (F508del homozygous), likely due to a change in chromatin state due to culturing/immortalization.