CFBE cells with flip-in site -- No CFTR construct introduced.
Homo sapiens
These cells contain a flip-in site for introducing a construct of interest. This sample has a flip-in site within an open chromatin region of chromosome 8. Other cell lines in this same project incorporate varying forms of CFTR into this site, but this sample only contains an empty flip-in site (negative control). This cell line does not endogenously express CFTR, likely due to a change in chromatin state due to culturing/immortalization.