CFBE cells with flip-in site -- G551D CFTR
Homo sapiens
These cells contain a flip-in site for introducing a construct of interest. This sample has a flip-in site within an open chromatin region of chromosome 8. This cell line incorporated G551D CFTR into this site. This cell line does not endogenously express CFTR, likely due to a change in chromatin state due to culturing/immortalization.