Escherichia coli
d-cycloserine
strain
WO153
isolate
NA
host
NA
isolation_source
NA
collection_date
2016/2018
geo_loc_name
NA
altitude
NA
biomaterial_provider
NA
culture_collection
NA
depth
NA
env_broad_scale
NA
genotype
NA
host_tissue_sampled
NA
identified_by
NA
lab_host
NA
lat_lon
NA
mating_type
NA
passage_history
NA
samp_size
NA
serotype
NA
serovar
NA
specimen_voucher
NA
temp
NA
sample_type
cell culture
id_espinoza-et-al
d-cycloserine|water-10|1|2|10.0|30|s30
run
10.0
id_jira
SOLEXASEQ-1137
id_orourke-et-al
R10_Cycloserine_BR2
id_sequencing-number
S30
id_barcode-number
30
biological_replicate
2
sample-category
pure_compound
sample-category_encoding
1
cpd_local
d-cycloserine
cpd_universal
d-cycloserine
ctrl_local
water-10
ctrl_universal
water
og_moa
cell-wall
moa
cell-wall
moa_encoding
3
moa_color
#d3db57
jcvi_sub-moa
peptidoglycan-precursor-formation
jcvi_sub-moa_encoding
3.0
neu_sub-moa
peptidoglycan-precursor-formation
neu_sub-moa_description
inhibits enzymes in peptidoglycan synthesis (alanine racemase, D-ala D-ala ligase, D-aa transaminase)
neu_sub-moa_encoding
3.0
gene_target_identifiers
['P0A6J8', 'Q9L888']
gene_target_description
competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis
ORourke_et_al
True
Espinoza_et_al
True
BioSampleModel
Microbe, viral or environmental