Mus musculus domesticus
Healthy mice with Rb1 floxed Rbl1 null Pten floxed Trp53 floxed genotype
breed
mixed breed FVB enriched
age
396
sex
female
tissue
Tail
biomaterial_provider
CIEMAT, 40th Complutense Av, Madrid, 28050
birth_date
2012-12-28
birth_location
Animal Facilities, CIEMAT, 40th Complutense Av, Madrid, 28050
breeding_history
Rb1 floxed Rbl1 null Pten floxed Trp53 floxed mice were generated by breeding Trp53 floxed Pten floxed (1) mice with Rb1 floxed Rbl1 null mice (2). (1) Costa C, et al. (2012) A novel tumor suppressor network in squamous malignancies. Sci Rep. doi:10.1038/srep00828. (2) Moral M, et al. (2009) Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma. Cancer Res. doi:10.1158/0008-5472.CAN-08-3240.
collected_by
Mirentxu Santos Lafuente, Miriam Perez Crespo, Sara Lazaro Encinas
collection_date
2014-01-28
death_date
2014-01-28
disease
None
disease_stage
None
genotype
Rb1 floxed Rbl1 null Pten floxed Trp53 floxed
geo_loc_name
Spain: Madrid
health_state
Healthy
sample_type
Tissue sample
store_cond
Tissue sample was stored in RNAlater at -20 C degrees for not loger than 6 months
treatment
None
BioSampleModel
Model organism or animal