Escherichia coli
ciprofloxacin
strain
WO153
isolate
NA
host
NA
isolation_source
NA
collection_date
2016/2018
geo_loc_name
NA
altitude
NA
biomaterial_provider
NA
culture_collection
NA
depth
NA
env_broad_scale
NA
genotype
NA
host_tissue_sampled
NA
identified_by
NA
lab_host
NA
lat_lon
NA
mating_type
NA
passage_history
NA
samp_size
NA
serotype
NA
serovar
NA
specimen_voucher
NA
temp
NA
sample_type
cell culture
id_espinoza-et-al
ciprofloxacin|naoh-6|1|3|6.1|3|s3
run
6.1
id_jira
SOLEXASEQ-1042
id_orourke-et-al
R06_Ciprofloxacin_BR3
id_sequencing-number
S3
id_barcode-number
3
biological_replicate
3
sample-category
pure_compound
sample-category_encoding
1
cpd_local
ciprofloxacin
cpd_universal
ciprofloxacin
ctrl_local
naoh-6
ctrl_universal
naoh
og_moa
dna-gyrase
moa
dna-synthesis
moa_encoding
5
moa_color
#57db5f
jcvi_sub-moa
dna-enzyme-inhibition
jcvi_sub-moa_encoding
1.0
neu_sub-moa
dna-enzyme-inhibition
neu_sub-moa_description
inhibit DNA gyrase and topo IV (linking them to DNA), leading to blocking of replication fork and eventual DNA strand breaks
neu_sub-moa_encoding
1.0
gene_target_identifiers
['P0AES4', 'P0C1U9', 'C3T8E2']
gene_target_description
DNA synthesis, DNA gyrase subunit A, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, Multidrug resistance protein MdtK
ORourke_et_al
True
Espinoza_et_al
True
BioSampleModel
Microbe, viral or environmental