Xenopus laevis
The establishment of cell lineages occurs via a dynamic progression of gene regulatory networks that underlie developmental commitment and differentiation. To investigate how microRNAs (miRs) function in this process, we compared miRs and miR targets at the initiation of the two major ectodermal lineages in Xenopus. We used next-generation sequencing to identify over 400 miRs expressed in midgastrula ectoderm expressing either noggin or a constitutively active BMP receptor.
breed
NXR
dev_stage
mid-gastrula
sex
not applicable
tissue
animal caps
collected_by
A.K.S.
BioSampleModel
Model organism or animal