CGFF2
Nakaseomyces glabratus
Alias
CGFF2
Description
In this work a phenotypic screening over a cohort of clinical Candida glabrata isolates was undertaken leading to the identification of an isolate, named FFUL887, which was recovered from the urinary tract and that was found to be resistant to both fluconazole and voriconazole. To better understand the molecular mechanisms underlying the azole-resistance phenotype of the FFUL887 strain its genome sequence was obtained, annotated and compared with the one of the reference strain CBS138, susceptible to the two above mentioned azoles and having an intestinal origin. Besides providing clues to mechanisms underlying acquisition of azole resistance inside the host, our results also provide insights into the different responses evolved by C. glabrata in the colonization of different niches.
ENA checklist
ERC000011
INSDC center name
Technische Universitat Munchen - WZW
INSDC first public
2017-10-23T17:03:30Z
INSDC last update
2017-02-15T12:23:42Z
INSDC status
public
SRA accession
ERS1559825
Sample Name
ERS1559825
Title
Sequencing and comparative genomics of Candida glabrata isolate FFUL887
isolate
FFUL887