Updated reference genome sequence and annotation of Mycobacterium bovis AF2122/97
Mycobacterium tuberculosis variant bovis AF2122/97
We report an update to the reference genome sequence of the bovine tuberculosis bacillus Mycobacterium bovis AF2122/97 generated using an integrative multi-'omics approach. Updates include 42 new coding sequences, 14 modified annotations, 26 single nucleotide polymorphisms and disclosure that the RD900 locus, previously described as absent from the M. bovis AF2122/97 genome, is in fact present.
ENA first public
2016-12-06
ENA last update
2016-11-30
External Id
SAMEA18127168
INSDC center alias
School of Veterinary Medicine
INSDC center name
School of Veterinary Medicine
INSDC first public
2016-12-06T17:02:11Z
INSDC last update
2016-11-30T15:40:39Z
INSDC status
public
Submitter Id
AF2122_1_R1
collection date
1997
geographic location (country and/or sea)
United Kingdom
host health state
diseased
host scientific name
Bos taurus
isolate
AF2122/97
isolation source
This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection.
sample name
AF2122_1_R1