Whole exome sequencing of colon tumors derived from Apc (Min716/+) transgenic mice (n=10)
Mus musculus
4-week-old Apc (Min716/+) transgenic mice were orally inoculated with vehicle control (VC) and euthanized at 12 weeks old. Upon sacrifice, colon tumors were derived, and genomic DNA was isolated using NucleoSpin Tissue Kit (Macherey-Nagel). Illumina DNA libraries with mouse exome capture were prepared using SureSelect Mouse All Exon Kit (Agilent), and sequenced using an Illumina NovaSeq6000 S4 System with 200x base coverage.
strain
C57BL/6 background
age
12 weeks
sex
male
tissue
colon tumor
disease
colon cancer
genotype
Apc (Min716/+)
sample_type
mouse tumor genomic DNA exome capture
sample_number
10
BioSampleModel
Model organism or animal