Whole exome sequencing of colon tumors derived from Apc (Min716/+) transgenic mice (n=13)
Mus musculus
4-week-old Apc (Min716/+) transgenic mice were orally inoculated with delta-ushA Citrobacter rodentium (dUA CR) and euthanized at 12 weeks old. Upon sacrifice, colon tumors were derived, and genomic DNA was isolated using NucleoSpin Tissue Kit (Macherey-Nagel). Illumina DNA libraries with mouse exome capture were prepared using SureSelect Mouse All Exon Kit (Agilent), and sequenced using an Illumina NovaSeq6000 S4 System with 200x base coverage.
strain
C57BL/6 background
age
12 weeks
sex
male
tissue
colon tumor
disease
colon cancer
genotype
Apc (Min716/+)
sample_type
mouse tumor genomic DNA exome capture
sample_number
13
BioSampleModel
Model organism or animal