Homo sapiens
This study aimed to investigate the miRNA's expression profile in order to identify possible biomarkers of colorretal cancer. We applied next generation sequencing to investigate the global expression profile of miRNAS from tissue samples of patients with cancer and external controls. 22 collected samples (7 patients' tissue, 7 patient's adjacent-tissue and 8 external controls) were prepared to be explored and passed a quality control pipeline (Trimmomatic software) and an alignment (STAR software) and read's count (HTSeq software) processes to perform differential expression (DESeq package), target genes (miRTarbase database), gene set enrichment (DAVID and Reactome databases) and miRNA-gene network analysis.
ENA-FIRST-PUBLIC
2021-03-01T12:39:26Z
ENA-LAST-UPDATE
2020-03-02T15:43:23Z
External Id
SAMEA6598957
INSDC center name
UFPA
INSDC first public
2021-03-01T12:39:26Z
INSDC last update
2020-03-02T15:43:23Z
INSDC status
public
Submitter Id
ERS10
bio material
Sigmoid-colon tissue
common name
human
environmental sample
Yes
geographic location (region and locality)
BRA-NE
sample name
ERS10
scientific_name
Homo sapiens
tissue type
Control