BCR-ABL inhibitor-resistant KCL-22 single clone #3
Homo sapiens
source_name
Blood (chronic myeloid leukemia in blast crisis)
cell line
CML cell line KCL-22
treatment
Single clone was isolated from 2.5 µM imatinib-resistant ClonTracer-barcoded KCL-22 subpopulation and expanded. This clone is never exposed to allosteric BCR-ABL inhibitors.
resistant to
2.5 µM imatinib/0.3 µM nilotinib