Rattus norvegicus
isolate
replicate-After routine skin sterilization and preparation, a small incision (~25 mm) was made on the left side of the midline of the neck. A small incision was made in the ECA and a silicone-coated MCAO plug carefully inserted into the middle cerebral artery via the ICA until slight resistance stopped the embolization. After 2 h of ischemia, the plug was removed for reperfusion. MCAO surgery led to infarction of the left middle cerebral artery in rats. To exclude the effect of the surgical procedure on neurobehavior of rats
breed
Sprague-Dawley rats
age
89-week-old
dev_stage
5
sex
male
tissue
cerebral cortex
BioSampleModel
Model organism or animal