Metagenome-assembled genome: SRR1779153_bin.8_CONCOCT_v1.1_MAG
Streptococcus peroris
This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run SRR1779153 of study SRP052967.
ENA-FIRST-PUBLIC
2023-01-03
ENA-LAST-UPDATE
2023-01-03
External Id
SAMEA14085584
INSDC center alias
EBI
INSDC center name
European Bioinformatics Institute
INSDC first public
2023-01-03T00:33:24Z
INSDC last update
2023-01-03T00:33:24Z
INSDC status
public
Submitter Id
SRR1779153_bin.8_CONCOCT_v1.1_MAG
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
metaspadesv3.10.0
binning parameters
Default
binning software
CONCOCT v1.1
broker name
EMG broker account, EMBL-EBI
collection date
2014-07-01
completeness score
64.87
completeness software
CheckM
contamination score
0.41
environment (biome)
Host-associated
environment (feature)
Human
environment (material)
Digestive system
geographic location (country and/or sea)
USA
geographic location (latitude)
40.4308
geographic location (longitude)
-79.9598
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
metagenomic source
human gut metagenome
project name
Premature infants are highly vulnerable to aberrant gastrointestinal tract colonization, a process that may lead to diseases like necrotizing enterocolitis. This study compares microbial communities of 10 co-hospitalized infants, five of which had a diagnosis of necrotizing enterocolitis. Surprisingly, while potentially pathogenic bacteria of the same species colonized many infants, a genome-resolved analysis revealed that strains colonizing each baby were typically distinct. In particular, no strain was common to all infants that developed necrotizing enterocolitis. The paucity of shared gut colonizers suggests the existence of significant barriers to spread of bacteria among infants. Importantly, we demonstrate that strain-resolved comprehensive community analysis can be accomplished on potentially medically-relevant time scales.
sample derived from
SAMN03295858
sample name
SRR1779153_bin.8_CONCOCT_v1.1_MAG
scientific_name
Streptococcus peroris
sequencing method
Illumina HiSeq 2000
taxonomic identity marker
multi-marker approach