Metagenome-assembled genome: ERR1913030_bin.29_CONCOCT_v1.1_MAG
uncultured Clostridia bacterium
This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR1913030 of study ERP019674.
ENA-FIRST-PUBLIC
2023-01-03
ENA-LAST-UPDATE
2023-01-03
External Id
SAMEA14083855
INSDC center alias
EBI
INSDC center name
European Bioinformatics Institute
INSDC first public
2023-01-03T00:33:14Z
INSDC last update
2023-01-03T00:33:14Z
INSDC status
public
Submitter Id
ERR1913030_bin.29_CONCOCT_v1.1_MAG
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
SPAdes genome assembler v3.11.1
binning parameters
Default
binning software
CONCOCT v1.1
broker name
EMG broker account, EMBL-EBI
collection date
2013-01-01
completeness score
76.44
completeness software
CheckM
contamination score
0.67
environment (biome)
Host-associated
environment (feature)
Human
environment (material)
Digestive system
geographic location (country and/or sea)
Germany
geographic location (latitude)
50.94291
geographic location (longitude)
6.967314
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
metagenomic source
human gut metagenome
project name
Parkinson's disease (PD) presently is conceptualized as a protein aggregation disease in which pathology involves both, the enteric and the central nervous system, possibly spreading from one to another via the vagus nerves. As gastrointestinal dysfunction often precedes or parallels motor symptoms, the enteric system with its vast diversity of microorganisms may be involved in PD pathogenesis. Alterations in the enteric microbial taxonomic level of L-DOPA-naïve PD patients might also serve as a biomarker.We thus compared the fecal microbiomes of 31 early stage, L-DOPA-naive PD subjects to 28 age matched controls by metagenomic analysis.
sample derived from
SAMEA103958153
sample name
ERR1913030_bin.29_CONCOCT_v1.1_MAG
scientific_name
uncultured Clostridia bacterium
sequencing method
Illumina HiSeq 2500
taxonomic identity marker
multi-marker approach