Metagenome-assembled genome: DRR014784_bin.92_CONCOCT_v1.1_MAG
uncultured Lachnospiraceae bacterium
This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run DRR014784 of study DRP001307.
ENA-FIRST-PUBLIC
2023-01-03
ENA-LAST-UPDATE
2023-01-03
External Id
SAMEA14080437
INSDC center alias
EBI
INSDC center name
European Bioinformatics Institute
INSDC first public
2023-01-03T00:33:00Z
INSDC last update
2023-01-03T00:33:00Z
INSDC status
public
Submitter Id
DRR014784_bin.92_CONCOCT_v1.1_MAG
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
metaspadesv3.12.0
binning parameters
Default
binning software
CONCOCT v1.1
broker name
EMG broker account, EMBL-EBI
collection date
not provided
completeness score
78.02
completeness software
CheckM
contamination score
4.39
environment (biome)
Host-associated
environment (feature)
Mammals
environment (material)
Digestive system
geographic location (country and/or sea)
not provided
geographic location (latitude)
not provided
geographic location (longitude)
not provided
investigation type
metagenome-assembled genome
isolation_source
gut metagenome
metagenomic source
gut metagenome
project name
Polyamines (PAs), such as putrescine, Spermidine, and spermine are related with cvarious bioactivity include strong anti-inflammatory function. Increasing PA concentration in intestine using probiotics; Bifidobacterium animalis subsp. lactis LKM512 caused inhibition of senescence and enhancing longevity of mice. We found that Arg intake also showed increase PAs concentration especially Putrescine. Mouse intakes Arg and LKM 512 resulted inhibited systemic inflammation, prolonged longevity, promoted spatial learning and memory. Metagenome analysis of intestinal mictobiota in those mice showed that detection of PA synthesis-related gene were different significantly between control and test mice.
sample derived from
SAMD00008873
sample name
DRR014784_bin.92_CONCOCT_v1.1_MAG
scientific_name
uncultured Lachnospiraceae bacterium
sequencing method
Illumina HiSeq 2000
taxonomic identity marker
multi-marker approach