Mus musculus
isolate
MC38 tumor cells were implanted subcutaneously into the Acsl4-cKO (Acsl4f/f Cd4cre) mice, then were given SM by intratumoral injection every other day. Tumor-infiltrating CD8+ T-cells were isolated by flow cytometry and centrifuge for ATAC-seq.
breed
Acsl4f/f Cd4cre mice (Acsl4-cKO)
age
not collected
sex
pooled male and female
tissue
CD8+ TILs isolated from subcutaneous MC38 tumors
biomaterial_provider
the Center for New Drug Safety Evaluation and Research, China Pharmaceutical University
treatment
Tumor-infiltrating CD8+ T-cells were isolated, centrifuged at 2000 rpm in cold PBS for 10 min and resuspended in 1 mL cold lysis buffer. ATAC-seq data analyses were performed by DIATRE Biotechnology (Shanghai, China).
BioSampleModel
Model organism or animal