Homo sapiens
For S70, allelic skewing is observed for the gene TNNI1. Specifcally, ~96% of the RNA transcribed for TNNI1 is observed to have a maternal variant (c.41G>A; p.R14H) located in exon 4 compared to ~4% of RNA that have a paternal inherited 7bp extension at the 5 end of exon 6. This extension results in in the introduction of the c.190-9G>A variant rendering a premature stop codon and nonsense mediated decay of the paternal allele.