binned metagenome: spire_mag_02411423
Bacteroides uniformis
ENA first public
2024-09-20
INSDC center name
EMBL Heidelberg
INSDC status
public
Submitter Id
spire_mag_02411423
assembly quality
Many fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly software
megahit 1.2.9
binning parameters
default
binning software
metabat 2.12.1
broad-scale environmental context
human digestive system
broker name
EBI-EMG
collection date
2011-02-01
completeness score
86.45
completeness software
checkm2 0.1.3
contamination score
0.7
environmental medium
stool
geographic location (country and/or sea)
Thailand
geographic location (latitude)
16.40000000
geographic location (longitude)
102.80000000
investigation type
metagenome-assembled genome
isolation_source
human gut metagenome
local environmental context
human gut
metagenomic source
human gut metagenome
project name
Recent development in intestinal microbiology has revealed crucial functions of gut microbiota as interface between diet and health and the question has arisen how diet modulates gut microbial community. In this context, Asia is an interesting association of cohorts with their own food habit unique to each country or region. To investigate the correlation among diet, health, and gut microbiota, Asian Microbiome Project (AMP) has been established with ten countries and Phase I study was already performed by focusing on children gut microbiota, which were expected to more depend on regional food compared to adult. Their microbiota has been analyzed based on 16S rRNA gene sequencing. As a result, we have found two distinctive enterotypes, Bifidobacterium/Bacteroides (BB) enterotype and Prevotella (P) enterotype in these Asian population, as well as local differences unique to each country or region. BB-enterotype was enriched in temperate countries, such as Japan and China, while P-enterotype was frequent in tropical countries. In conjunction with dietary survey, it is suspected that these difference may be a reflection of their dietary habit. To correlate the function of their gut microbial community with diet input, we performed shotgun metagenomic sequencing of those microbial community and gained overview on consortium of functional genes, e.g., network of anabolic and catabolic pathway enriched in each food-oriented enterotype or biosynthesis of beneficial or non-benefical compounds, such as vitamins or secondary bile acids.
sample derived from
SAMD00046807
sample name
spire_mag_02411423
scientific_name
Bacteroides uniformis
sequencing method
Illumina HiSeq 2500
taxonomic identity marker
multi-marker approach